Quality Control Challenges and Vaccine Manufacturing

Sweta S Kumar; Bhagat Singh; Rishi Kumar Singh; Ramakant Yadav; Shashidhar Mehta; Harsh Pratap Singh

doi:10.54618/IJMAHS.2022242

Sweta S Kumar Associate professor, Department of Dermatology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, 206130, U.P, India
Bhagat Singh Department of Medical Lab. Technology, U P University of Medical Sciences, Saifai Etawah-206130, India
Rishi Kumar Singh Associate Professor, Dept. Microbiology, School of Biosciences, IMS-Ghaziabad, Uttar Pradesh- 201015 India
Ramakant Yadav Department of Neurology, UP University of Medical Sciences, Saifai, Etawah-206130, India
Shashidhar Mehta Department of Biochemistry, Clinical Research Centre, Vallabhbhai Patel Chest Institute, University of Delhi, India
Harsh Pratap Singh Department of Physics, Indian Institute of Technology, Delhi-110016 New Delhi, India

DOI: https://doi.org/10.54618/IJMAHS.2022242

Keywords: Vaccine, mRNA and pDNA Vaccines, Vector vaccine, Quality control

Abstract

Every year vaccines save millions of lives worldwide resulting in development of global health. The mechanism how vaccines work can be understood that they stimulate or induce the host cells responsible for natural defence system thereby our body can recognize and fight off the target microorganisms including viruses and bacteria. After vaccination once immunity is established, further exposure is detected by immune cells ready to fight disease-causing microorganisms targeted for, and hence preventing from developing sever illness. For helping people by preventing from about 20 disease that could be life threatening, vaccines are available. Immunization is preventing about 3.5-5 million deaths every year. WHO immunization agenda 2030 (IA2030) have the vision and strategy for the decade 2021-2030 for vaccines and immunization.