Eco-Friendly Synthesis of Pyrazoline Derivatives

  • Mahesh G. Kharatmol Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, CBD Belapur, Navi Mumbai, Maharashtra, India 400614.
  • Deepali M. Jagdale Department of Pharmaceutical Chemistry, Bharati Vidyapeeth’s College of Pharmacy, CBD Belapur, Navi Mumbai, Maharashtra, India 400614.
Keywords: Green synthesis, Chalcone, Pyrazoline, Microwave Irradiation, Ultrasonic Irradiation, Grinding Method, Ionic Liquids.

Abstract

Pyrazoline class of compounds serve as better moieties for an array of treatments, they have antibacterial, antifungal, anti-inflammatory, antipyretic, diuretic, cardiovascular activities. Apart from these they also have anticancer activities. So, pertaining to its importance, many attempts are made to synthesize pyrazolines. Since conventional methods of organic synthesis are energy and time consuming. There are elaborate pathways for green and eco-friendly synthesis of pyrazoline derivatives including microwave irradiation, ultrasonic irradiation, grinding and use of ionic liquids which assures the synthesis of the same within much lesser time and by use of minimal energy.
Published
2017-04-25