In-Vitro Anti-Diabetic Activity of Ficus krishnae Stem Bark Extracts

Ramesh L Londonkar; Amarvani P Kanjikar; Aruna L H

Ramesh L Londonkar Department of Biotechnology, Biopharmaceutical and Nanobiotechnology Laboratory, Gulbarga University, Kalburagi, India
Amarvani P Kanjikar Department of Biotechnology, Biopharmaceutical and Nanobiotechnology Laboratory, Gulbarga University, Kalburagi, India
Aruna L H Department of Biotechnology, Biopharmaceutical and Nanobiotechnology Laboratory, Gulbarga University, Kalburagi, India

Keywords: Ficus krishnae, soxhlet extract, anti-diabetic, alpha amylase.

Abstract

Ficus krishnae (Moraceae) is one of the folklore medically important native plant to India. It has been used extensively by ayurvedic practitioner in India to treat various ailments such as ulcers, vomiting, fever, inflammations, leprosy, syphilis, biliousness, dysentery and inflammation of liver. The present study aims the screening of Ficus krishnae stem bark extracts for in-vitro anti-diabetic study. The in vitro alpha-amylase inhibitory study was performed using different concentration of extract and compared with a standard drug. The results reveal that, there was a dose dependent increase in the percentage inhibitory activity against intestinal enzymes by petroleum ether, chloroform and aqueous extracts. Our findings suggests that the petroleum ether extract and acarbose have an efficient anti-diabetic activity.