Self-Assembling Peptides- Notion and Medical Applications: A Review

D V Gowda; Anoojnya Sharma; N Vishal Kumar Gupta; Riyaz Ali M Osmani

D V Gowda Department of Pharmaceutics, JSS College of Pharmacy, Jagadguru Sri Shivarathreeshwara University, S.S. Nagara, Mysuru-570 015, Karnataka, India
Anoojnya Sharma Department of Pharmaceutics, JSS College of Pharmacy, Jagadguru Sri Shivarathreeshwara University, S.S. Nagara, Mysuru-570 015, Karnataka, India
N Vishal Kumar Gupta Department of Pharmaceutics, JSS College of Pharmacy, Jagadguru Sri Shivarathreeshwara University, S.S. Nagara, Mysuru-570 015, Karnataka, India
Riyaz Ali M Osmani Department of Pharmaceutics, JSS College of Pharmacy, Jagadguru Sri Shivarathreeshwara University, S.S. Nagara, Mysuru-570 015, Karnataka, India

Keywords: Amino Acids, Peptides, Drug Delivery, Applications, Diagnosis, Therapy.

Abstract

Peptides are the building blocks which are widely used owing to their biology as well as their chemistry. They provide a vast platform in the area of medicine. Self-assembling peptides are peptide biomaterials which are pacing in the field of diagnosis, therapeutics, tissue regeneration and vaccine. Self-assembling peptides provide an excellent alternative to the conventional methods for the drug delivery and the treatment. In this article, we discuss about the various medical applications of self-assembling peptide as they have excellent biocompatibility and resemblance with the proteins in the biological system. These are constructed and modified using various amino acid sequences depending upon the type of the application for which it is being used.