A Recent Progresses and Manufacturing Techniques in Pharmaceutical Powders and Granulation

Rasha Saad Suliman; Heyam Saad Ali; Babiker M A Elhaj; Raina Suliman

Rasha Saad Suliman College of Pharmacy, King Saud bin Abdulaziz University for Health Sciences Ministry of National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia
Heyam Saad Ali Department of Pharmaceutics and Pharmacy Practice, Dubai Pharmacy College, Dubai, United Arab Emirates
Babiker M A Elhaj Pharmaceutical Sciences, College of Pharmacy Ajman University of Science and Technology.
Raina Suliman College of Sciences, Princess Nourah Bint Abdulrahman University.

Keywords: Pharmaceutical Manufacturing Techniques, Powders and Granulation Pharmaceutical dosage forms.

Abstract

Nowadays very few drugs are formulated as powders or granules, they are usually taken with some water in which they are readily dispersible in and somewhat rapidly dissolving in as a result of the large surface area provided by the small particles of the powder as well as high solubilitys of the other ingredients used in the formulation, leading to high drug absorption, their bioavailability could be similar to the suspensions form in general. This review covers the classifications of pharmaceutical powders, and recent advancements in granulation techniques with their desirable characteristics in enhancing drug bioavailability and manufacturing performance.