Overview of Antibiotic Therapy to Methicillin Resistant Staphylococcus Aureus (MRSA)

Tale V S; Das Sarkar D

Tale V S Rajiv Gandhi Institute of IT and Biotechnology, Bharati Vidyapeeth (Deemed to be) University, Pune, Maharashtra 411046
Das Sarkar D Rajiv Gandhi Institute of IT and Biotechnology, Bharati Vidyapeeth (Deemed to be) University, Pune, Maharashtra 411046

Keywords: methicillin, Staphylococcus aureus

Abstract

Multidrug resistant Staphylococci are considered to be a major issue in human health. The MRSA strains shows great resistance to most commonly used antibiotics such as Aminoglycosides, Microlides,Fluoroquinolones and Chloramphenicol etc. Strains of S.aureus when recognized as MRSA,it is placed under the category of MDR and are labeled as superbug in the health domain.The genomic island Staphylococcal cassette chromosome make (SCC mec) contains the antibiotic resistant gene mec A along with Cytolycin gene psm-mec. High usage of antibiotics in hospitals with selection pressure of the antibiotics has led to the development of multidrug resistance (MDR) in hospital acquired MRSA (HA-MRSA) strains.