Correlation Between the Dopamine and ROS Levels in Depression Disorders

Abstract

Depression is one of the mode disorder diseases which recorded in high percentage in last years in the Iraqi population. The current study suggested to determine the correlation between dopamine level with reactive oxygen species (ROS) in depressed patients, results exhibit that ROS was higher in depressed patients than control in significant differences (p 0.000), dopamine decreased in patients in comparing with control in non-significant differences (p 0.273). The correlations among study variables in patient group were non-significant weak positive correlation between age and dopamine (r 0.033, p 0.894), non-significant inverse relation between BMI and dopamine (r -0.297, p 0.217), non-significant inverse weak correlation observed between Dopamine and ROS (r-0.069, p 0.780). The correlation between ROS and age was an inverse correlation (r -0.060, p 0.808) and with BMI weak positive correlation (r 0.190, P 0.790) in non-significant differences in both variables. In the control group the correlation between age and dopamine non-significant weak positive relation was observed (r 0.098, p 0.691). Non-significant inverse relation between BMI and dopamine (r -0.062, P 0.801), non-significant inverse weak correlation observed between Dopamine and ROS (r-0.064, p 0.794). The correlation between ROS and age was an inverse correlation (r -0.018, p 0.940) and with BMI inverse correlation (r -0.417, p 0.075) in non-significant differences in both variables. The current results concluded that the dopamine was slightly affected by ROS, age and BMI in depression patients.