Antioxidant Activity of the Successive Extracts of Aesculus indica Leaves

Guno Sindhu Chakraborthy

doi:10.25004/IJPSDR.2009.010216

Guno Sindhu Chakraborthy Department of Pharmacognosy, SVKM’s, NMiMS university, School of Pharmacy and Technology Management, Shirpur Campus, Maharashtra, India, 425 405.

DOI: https://doi.org/10.25004/IJPSDR.2009.010216

Keywords: Aesculus indica, Antioxidant, DPPH, Nitric Oxided, Peroxidation, Free radical scavenging.

Abstract

Plants are the best source of active secondary metabolites which are beneficial to mankind. Many plant origin drugs have been reported with biological properties like Analgesic, Anti-inflammatory, Antioxidant, hypoglycemic agents and many more. The successive extracts of Aesculus indica leaves were screened for in vitro antioxidant properties using the standard procedures. The successive extracts such as petroleum ether, ethyl acetate, methanol and water and 50% crude methanol extracts exhibited IC 50 values of respectively in DPPH and respectively in nitric oxide radical inhibition assays. The values are comparable with the standards such as ascorbic acid and quercetin. The Aesculus indica leaves are showing significant antioxidant activity.