Sub-Acute Toxicity Study of Etimicin Sulphate in Wistar Rat.

Anurag Payasi; Manu Chaudhary; Anupama Tamta; Vivek K. Dwivedi

doi:10.25004/IJPSDR.2010.020207

Anurag Payasi Office of Research Support, Research & Development Centre, Venus Medicine Research Centre, Hill Top Industrial Estate, Bhatoli Kalan, Baddi, Himachal Pradesh - 173205 India.
Manu Chaudhary Office of Research Support, Research & Development Centre, Venus Medicine Research Centre, Hill Top Industrial Estate, Bhatoli Kalan, Baddi, Himachal Pradesh - 173205 India.
Anupama Tamta Office of Research Support, Research & Development Centre, Venus Medicine Research Centre, Hill Top Industrial Estate, Bhatoli Kalan, Baddi, Himachal Pradesh - 173205 India.
Vivek K. Dwivedi Office of Research Support, Research & Development Centre, Venus Medicine Research Centre, Hill Top Industrial Estate, Bhatoli Kalan, Baddi, Himachal Pradesh - 173205 India.

DOI: https://doi.org/10.25004/IJPSDR.2010.020207

Keywords: Toxicity, Rat, Blood, Etimicin sulphate.

Abstract

The aim of the present study was to evaluate subacute toxicity of etimicin sulphate on wistar rat. Results from the present study have elucidated that treatment of etimicin sulphate exerts no significant signs of toxicity at any dose level used in the study. Physical, biochemical as well as hematological parameters was unaltered throughout the study. Histopathology of all organs confirmed no significant alteration at any dose levels. The results of study have suggested there was no obvious toxicity observed with the treatment of etimicin sulphate. It was found to be safe alternative for various severe infections.