https://myresearchjournals.com/index.php/IJSTS/issue/feed 2021-09-20T05:52:39+02:00 Shubhini A. Saraf [email protected] Open Journal Systems <table border="0" width="100%"> <tbody> <tr> <td valign="top"><strong>Publisher:</strong>&nbsp;BABASAHEB BHIMRAO AMBEDKAR UNIVERSITY</td> </tr> <tr> <td valign="top"><strong>Editor-in-Chief:&nbsp;</strong>Professor&nbsp;Shubhini A. Saraf</td> </tr> <tr> <td valign="top"><strong>No. of Issues Per Year:</strong>&nbsp;2&nbsp;&nbsp;&nbsp;|&nbsp;&nbsp;&nbsp;<strong>Frequency:</strong>&nbsp;Bi-annual</td> </tr> <tr> <td valign="top"><strong>Print ISSN:</strong>&nbsp;2395-1605 |&nbsp;<strong>Online ISSN:</strong>&nbsp;2395-7395</td> </tr> <tr> <td valign="top"><strong>Indexed with:</strong>&nbsp;Ulrich's.</td> </tr> </tbody> </table> https://myresearchjournals.com/index.php/IJSTS/article/view/6271 2021-09-20T05:52:38+02:00 Irfan Aziz [email protected] Rishabh Chaudhary [email protected] Vikas Mishra [email protected]

The World Health Organization (WHO) officially confirmed COVID-19 as a viral pandemic caused via SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Novel coronavirus disease 2019 (COVID- 19) is an extremely pathogenic and transmissible infection induced by a virus named SARS-CoV-2. SARS-CoV-2 is a single-stranded positive- sense ribonucleic acid (RNA) virus. Genomic analysis has shown that SARS-CoV-2 is phylogenetically analogous to SARS-like viruses. It primarily effects on both upper and lower respiratory tract system. Pneumonia is a typical feature of the SARS-CoV-2 infected individuals. Numerous therapeutic drugs are presently being used alone or in combination along with other drugs to overcome this disease. The purpose of this review is primarily to present an outline of the origin, classification, possible reservoirs and biological morphology of the SARS-CoV-2 virus. It also outlines the emerging diagnostic and therapeutic treatment approaches for COVID-19.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6272 2021-09-20T05:52:38+02:00 Santosh Gupta [email protected] Parul Atri [email protected] Shubhra Bhatia [email protected]

The real estate sector is one of the most important sectors of our Indian economy. It is expected that the Indian real estate sector will reach US$ 1 trillion by the end of 2030. Since it has a very high multiplier impact on the economy therefore, it has proved to be a big driver of economic growth as well. After agriculture, this sector is the second-largest employment generating sector. The real estate industry in India has been growing at about 20% per annum and is contributing nearly 5-6% to Indian GDP. Besides generating high level of direct employment, it has also helped in stimulating the demand in more than 250 ancillary industries such as cement, steel, paint, brick, building materials, consumer durables and many more. Indirect taxability of Construction activities has been tough always and also subject to litigation many a times. Prior to Goods and Services tax (‘GST’) rules, the real estate developers and the buyers had to deal with problems arising from manifold erstwhile taxes such as VAT, Service Tax, Central Excise, Octroi, Entry Tax, Local Body Taxes, etc. In addition, rates of specific state, deemed sales, different valuation for VAT and Service tax, and varied schemes for paying taxes etc. were among the major problems faced by real estate sector. Before GST was introduced in India, the Central Government levied excise duty of 12.5% on almost all the items required for real estate construction. Parallelly, the State Governments charged value-added tax (‘VAT’) from 12.5% to14.5% on the same products. This study aims at researching the detailed impact of GST on the Indian Real Estate Sector.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6273 2021-09-20T05:52:38+02:00 Alok Kumar [email protected] Pradyumn Singh [email protected] Anshuman Pandey [email protected] Gosipatala Sunil Babu [email protected]

Colorectal cancer (CRC) is the third most common cancer worldwide with 1.3 million new cases each year. In India, it is the fourth most common cancer in males and the third most common cancer in females. By the advent of molecular biology techniques, new biomarkers such as methylation of DNA, miRNAs resulted and used for early diagnosis as well as personalized therapies. Tumor suppressor gene(s) promoter methylations are one of such biomarkers in identifying the tumor aggressiveness, metastasis and the survival outcome after the surgery. Suppressor of cytokine signaling-1 (SOCS1) gene is a tumor suppressor gene, reported to be silenced in several types of cancers including CRC. However, the role of SOCS1 promoter methylation as a marker remains understudied, not completely established in CRC. We investigated the promoter methylation status of SOCS1 gene in stage II and III CRC samples, find its prognostic significance and association with clinicopathological characteristics. We analyzed 56 CRC samples for SOCS1 promoter methylation and found, 24 samples (42.9%) methylated whereas 32 samples (57.1%) unmethylated. The pathological investigations revealed that SOCS1 promoter methylations were associated with poor differentiation of tumor tissue (P less than 0.017), and decreased the overall survival rate (22.5 months). Further, we also found that promoter methylations are not associated with other clinicopathological characteristics such as lymph node metastasis, tumor stage, and dietary habits.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6274 2021-09-20T05:52:38+02:00 Marziya Rizvi [email protected] Husnu Gerengi [email protected]

The inhibition properties of galactomannans (GM) on low carbon steel samples immersed in 1M HCl were judged by advanced electrochemical assessments. The electrochemical results obtained by potentiodynamic polarization and electrochemical impedance spectroscopy of the inhibited electrodes were evaluated in contrast to the electrodes prone to corrosive solution and GM’s character in inhibition of corrosion was perceived. The results, qualitative and quantitative thus derived prove GM to be effective for corrosion protection of SAE 1010 carbonsteel in 1 M HCl.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6275 2021-09-20T05:52:39+02:00 Farheen Khan [email protected] Samipta Singh [email protected] Ravi Raj Pal [email protected] Raquibun Nisha [email protected] Malti Arya [email protected] Poonam Parashar [email protected] Priyanka Maurya [email protected]

Nanostructured lipid carriers (NLC) are a new progression in the area of lipid nanoparticles which are preferred for topical use. NLC possess reasonable solubility enhancement capacity of poorly soluble drugs, which create a high concentration gradient to aid the permeation of drug. The endeavor of this study was to develop and analyze Physalis peruvianaoil based NLC. Theoilwas extracted by hot soxhlation using n-hexane as the solvent and the extracted oil wasutilized as an excipient (liquid lipid). Factorial design was adopted to optimize the amount of lipid blend (extracted oil and solid lipid), surfactant (Pluronic F-68) and sonication time to formulate NLC. The optimized formulations of fluconazole loaded NLC (PP-F-NLC) were evaluated by particle size, antifungal study, occlusion test, in-vitro skin permeation study and irritation test on animal skin. EE was found to be 99.96% and the optimized formulation showed 83% drug release in 24 hours. The formulated NLC showed better skin penetration, and potent antifungal activity against Microsporum fulvum as compared to marketed gel.It was concluded that the Physalis peruviana oil incorporated NLC is a promising formulation for fungal treatment and possesses high antioxidant potency.Physalis peruviana NLC can act as a potential carrier for anti-fungal/anti-inflammatory drugs to enhancethe purported pharmacological activity against various problems.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6276 2021-09-20T05:52:39+02:00 Vigya Mishra [email protected] Ashish Shukla3 [email protected] Kishan Raj [email protected] Anu Nawhal [email protected]

Muskmelon is a highly perishable fruit of summers. It is mainly consumed as table fruit and has least uses in processing industry. Being a good source of sugars, vitamins, minerals and due to its refreshing nature, musk melon is a popular fruit in summers. But due to high moisture content the fruit can’t be stored for a long duration resulting in high post harvest losses of the fruit. Banana is also a very good source of minerals and nutrients. Due to the climacteric nature, it ripens very fast and therefore, is highly perishable in nature. Overripe bananas, although being a rich source of sugar and calories are not consumed by people due to its poor and soggy texture. Efforts were made to develop fruit leather from musk melon to utilize its nutritional properties and reduce post harvest losses during summers. Over ripe bananas were used to sweeten the product. Muskmelon and over ripe banana were mixed in different proportions to prepare fruit leather. Treatment R4 (Muskmelon-90%, banana pulp-10%) was adjudged best,on the basis of overall acceptability and nutritional quality. It contained fair amount of ascorbic acid, carotenoids, total soluble solids and sugars. Fruit leathers were palatable, with good texture and flavour.Development of muskmelon-banana leather was found to be an innovative idea to blend the various nutritive properties of muskmelon and over ripe banana together to increase the consumption and usage of both muskmelon and over ripe banana.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6277 2021-09-20T05:52:39+02:00 Rubina Chaudhary [email protected] Rana Pratap Singh [email protected]

A Solidification/ Stabilization performance of lead containing battery waste slag with cement matrix was studied. The samples of an industrial battery waste slag were used in experimental work. Heavy Metal Characterization of battery waste slag by Atomic Absorption Spectrometry (AAS) revealed that battery waste slag contains a certain percentage of lead and Chromium. Dissolving of the slag components causes migration of ions into water that can induce a significant pollution of environment. The influence of concrete block composition was the evaluated for fly ash coated and without fly ash coated block. For Mandatory requirement also available leaching test [NEN- 7341] to evaluate the leaching behavior of coated and without coated concrete block. The result revealed that Unconfined Compressive Strength were observed in the range of 6.51- 25.66 mpa without coated concrete block and coated block with 2.9 mpa - 17.67 mpa.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6278 2021-09-20T05:52:39+02:00 Rubina Chaudhary [email protected] Sumit Devraye [email protected] Lalit Yadav [email protected]

The objective of this work was to comparatively investigate the performance of two anaerobic waste water treatment reactors namely UASB and fluidized Bed Reactor (FBR). Two lab scale models were erected and experiments were carried on both the reactors for different substrate concentration of COD 16800mg/L and 2880mg/L for UASB and FBR respectively. Effect of HRT on degradation of organic matter was studied through estimating COD at regular time intervals, COD removal rates for FBR and UASB were found to be 108mg/L/ day and 231mg/L/day respectively, The COD removal for UASB and FBR was 60% and 57% of the initial value respectively.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6279 2021-09-20T05:52:39+02:00 Krishan Kumar [email protected]

Open-source dataset available for different source of platform.Software quality is an important approach for the user as well as softwaredevelopers also.In this paper the study of various classification and regression tree (CART) method for software quality predictions. In this method have been used for a new algorithm design which is based on partitioning method. Among so many prediction methods over the recently published data mining predictionsfor software quality models such that classification and regression tree (CART), deep neural network (DNN), hierarchical attention network (HAN), multiple linear regression (MLR), stepwise regression (SR), artificial neural network (ANN) and case-based reasoning (CBR).CART algorithm to design an enhanced level of classification accuracy for large (complex) data set when compared with prior to classical CART concepts. CART can perform a balanced tree structure that is misclassify the fault-prone modules to classification-tree models based on Open-source dataset. The Open-source dataset used in Vote to classify the various machine learning algorithms such as J48, Random Forest, Logistic Model Tree. In this paper we also compute the best accuracy for vote dataset. This paper presents details on the cart algorithm to predict the quality of system in different ML algorithms.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/IJSTS/article/view/6280 2021-09-20T05:52:39+02:00 Aishwarya Kamya Singh [email protected]

This book comprises sixteen chapters compilation of research papers authored by different authorsdeliversall the information about surrogacy and ART (Assisted Reproductive Technology) and provides a deep knowledge about all the surrounding issues. This book gives overview about howsurrogacy and ARTarrangementhelps childless infertile couple to get the baby of their own. In this arrangement, egg fertilized with spermin lab and then inserted in surrogate womb. Information about various form of surrogacy and ART also covered in this book.But central point of this book revolves around socio-legal, ethical issues and dilemma related to Surrogacy and ART faced by India and other countries. This book provides about the complexities and the challenges faced by surrogacy in recent time. This book covers all aspects along with International and national legislation related to surrogacy, Judicial approaches and India surrogacy bill, complications surrounding surrogacy and ART.

2021-02-25T00:00:00+01:00 ##submission.copyrightStatement##