NANOTECHNOLOGY BASED DETECTION AND THERAPY OF OVARIAN CANCER

  • Manoj Kumar Baghel Department of Biotechnology, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara
  • Poonam Deore Department of Biotechnology, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara
  • Bhargavi Patel Department of Biotechnology, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara
  • Esha Rami Department of Biotechnology, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara
Keywords: Ovarian Cancer, Nanotechnology, Nanocarriers, Detection, Screening, Imaging, Theranostic

Abstract

Ovarian carcinoma is the leading reason behind death from gynaecologic malignancies, which could be a direct outcome of missing its diagnosis at an early stage. Nanotechnology has great promise in addressing existing problems to boost the diagnosis and therapy of Ovarian Cancer. Nanocarriers are multifunctional as several varieties of molecules are often loaded onto them through physical adsorption or chemical conjugations including drugs, imaging agents, targeting moieties like ligands or Antibodies. Present research for earlier detection of Ovarian Cancer focuses on identifying Ovarian Cancer biomarkers through developing a profile of aberrantly expressed molecules and by enhancing imaging techniques. This early detection will ultimately lead to a stronger prognosis and an increased survival rate. Also, Nanotechnology can improve screening for ovarian Cancer by fabricating lab-on-a-chip microfluidic devices for immuno-screening. Overall, the incorporation of nanotechnology into existing detection methods of Ovarian cancer demonstrates great promise in detecting the disease at an earlier stage. With the arrival of nanotechnology, it'll be possible to detect the previously undetectable concentrations of Ovarian Cancer biomarkers and visualize Ovarian Cancer cells in real-time.
Published
2020-04-30