PROGRESS IN THE PATHWAYS FOR SYNTHESIS OF ISOXAZOLES SYNTHONS AND THEIRBIOLOGICAL ACTIVITIES

Abstract

Isoxazole and its derivatives are one of the very important classes of heterocyclic compounds which displaying a broad spectrum of biological activities which have made them very important structures in the field of medicinal chemistry. Isoxazoles are clinically proven to be very active as antibacterial, antifungal, anti-inflammatory, anticancer, antitubercular and antineoplastic agents. The different derivatives of isoxazole which exhibits differences in the structure have shown a vast diversity in their medicinal properties which have proven them as very beneficial in the progress of novel therapeutic agents which shows enhanced effectiveness and minor harmfulness. Hence, because of this widespread research on isoxazole from so many years, due to this reason, it has become necessary to analyse new progress in the synthetic routes and widespread range of biotic activity of isoxazole. With this conclusion, the present evaluation will be useful for the novel drug discovery of isoxazole molecules.