GREEN SYNTHESIS OF TETRA-AZEPINES USING MICROWAVE ASSISTED METHOD

Abstract

Synthesis of tetra-azepines has been achieved by environmentally benign methods. In this dihydroformazan has been reacted with oxalic acid, ethylene glycol, chloro acetic acid etc. in microwave oven for about 1 to 2 minutes to yield tetra-azepines. All the products have been purified by crystallization and these have been acetylated and benzoylated by using acetic anhydride and benzoyl chloride to yield acetylated and benzoylated products respectively. The structure of all these synthesized compound have been established on the basis of elemental analysis and spectral data.