SYNTHESIS AND ANTIMICROBIAL STUDIES OF NEWLY SYNTHESIZED 1-SUBSTITUTED-3-SUBSTITUTED PROPANE-1, 3-DIONES

Sushil Pagariya; Rajendra Pathade; Ram Isankar; Pravin Bodkhe

Sushil Pagariya Department of Chemistry, Govt. Vidarbha Institute of Science and Humanities, Amravati, India
Rajendra Pathade Department of Chemistry, Govt. Vidarbha Institute of Science and Humanities, Amravati, India
Ram Isankar Department of Chemistry, Govt. Vidarbha Institute of Science and Humanities, Amravati, India
Pravin Bodkhe Department of Chemistry, Vidyabharati Mahavidyalaya, Amravati, India

Keywords: Propane-1, 3-diones,Vanillin, Spectral studies, Antimicrobial effects.

Abstract

In this current work, one new series of 1-Substituted-3-substitutedpropane-1, 3-diones or β-diketones 4(a-e) have been synthesized from 4-Hydroxy-3-methoxybenzaldehyde i.e. Vanillin. The structures of titled synthesized compounds of the series have been confirmed by usual chemical characteristics, elemental analysis, IR and NMR spectral studies. They have also been studied for their antimicrobial effects against the growth response of pathogenic microorganisms viz. E. coli, S. aureus, A. flavus through agar diffusion method.