https://myresearchjournals.com/index.php/JCKHH/issue/feed 2021-12-20T18:17:59+01:00 Global SciTech Ocean (GLOSTO) Publishing Co. [email protected] Open Journal Systems <p>Journal of Conventional Knowledge and Holistic Health (ISSN 2581-3331) (Abbreviation: J Convent Knowl Holist Health) is an international research journal dedicated to publish all type of Review articles, Min-review articles, Research articles, Short communications, Case reports, Letter to Editor, Book reviews and Commentaries in the all areas of conventional medical systems including Ayurveda, Siddha, Yoga, Homeopath and Unani systems of medicine, Chinese traditional medicine, Sowa Rigpa, African, European, American, Brazilian and Australian traditional medicinal systems, herbal medicines, bioactive natural products, quality control of herbal products, isolation and identification of plant-derived bioactive compounds, etc. The journal aims to publish high-quality papers in all areas of traditional and alternative medicine, integrative medicine and conventional knowledge by following a holistic approach.</p> https://myresearchjournals.com/index.php/JCKHH/article/view/1399 2021-12-20T18:17:59+01:00 N. Senthamizh [email protected] R. Vidhyavathi [email protected] E. Mohan Raj [email protected] Vijay Lobo [email protected] R. Arun Kumar [email protected]

Non-small cell lung cancer (NSCLC) is the prevailing kind of lung cancer. Molecular target has exceptionally improved the treatment viability of lung cancer, however, new difficulties have developed, for example, drug resistance and cancer repeat. Along these lines, new chemotherapeutic operators and treatment techniques are earnestly required. Reserpine, a natural indole alkaloid, is the fundamental dynamic piece of Indian restorative plant which has been appeared to show ground-breaking hostile to cancer action in specific kinds of cancer; be that as it may, its movement in drug-safe lung cancer has never been tended to. In this investigation, we utilized 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT) measure and 2,7-dichlorodihydrofluorescein diacetate (DCFH-DA) test to examine reserpine anticancer movement. The cytotoxicity of reserpine in NSCLC cell lines was profoundly investigated. Reserpine displayed specific cytotoxicity among NSCLC at 15, 25 and 35 μM concentrations. Reserpine essentially expanded the action of ROS, which are profoundly expanded apoptosis. Improved ROS, altogether initiated customized cell passing in human NSCLC cells. The upgrade of ROS age in drug-safe NSCLC cells prompts impedance of development and acceptance of apoptosis. In this way, reserpine-prompted cell apoptosis is firmly connected with ROS rise in the cells. These discoveries show that reserpine can be a powerful mix of treating drug-safe NSCLC.

2020-11-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/JCKHH/article/view/1400 2021-12-20T18:17:59+01:00 V. Kanchana [email protected] G. Venkat Kumar [email protected] R. V. Shalini [email protected]

The present study aimed to analyse the phytochemical and antibacterial activity of different extracts of the tropical plant Hamelia patens Jacq. (Rubiaceae). The antimicrobial activity was carried out using agar well diffusion method. Hexane, petroleum ether, ethanol and chloroform stem extracts (100 μL of 50 mg/mL each) were introduced into the wells separately and allowed it to undergo incubation. After the incubation time was over, the plates were observed for zones of inhibition and compared with positive control ciprofloxacin at a concentration of 30 μM. These results provided evidence that the tested plant extracts possess antimicrobial properties which can be tested further in the development of novel antimicrobial agents.

2020-11-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/JCKHH/article/view/1401 2021-12-20T18:17:59+01:00 Bhavana Vinayak Bhat [email protected] J. M. Nagaraja [email protected]

Dandruff, a scalp disorder, affects the population of worldwide which is although not a transmitted disease but caused a social or self-esteem problem. Itching and flakiness are the common causes of dandruff which can also affect the facial skin if not treated in time. As per Ayurveda texts, dandruff can be correlated with Darunaka and vata and kapha doshas might be responsible for its development. This study used a paste of khakasa beeja (Papaver somniferum) and godugdha (cow milk) to treat dandruff which is also mentioned in Ayurvedic Samhitas for the treatment of darunaka condition. A total of 60 patients have been enrolled for this study in which 30 patients were given above treatment while the rest of the 30 patients were treated with neem paste. The study suggested that the khakasa beej and godugdha paste has the potential to treat dandruff.

2020-11-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/JCKHH/article/view/1402 2021-12-20T18:17:59+01:00 Hayder M. Al-Kuraishy [email protected] Ali I. Al-Gareeb [email protected] Marta Chagas Monteiro [email protected] Heiam N. Hussein [email protected]

The coronavirus disease 2019 (Covid-19) epidemic, which originated in Wuhan, China, has now extended to more than 200 countries and administrative regions infecting nearly 36,792,906 individuals of all ages as of 9 October 2020. Many of these articles pursue to investigate the epidemiological parameters of the disease at different locations to disseminate critical information among both modellers and policymakers for a timely control response to be implemented. Iraq has had 394,566 confirmed cases with 9,683 deaths according to the last update registration of Iraq Ministry of Health. In the infected region, despite unusual efforts to limit the movement of people at the expense of the Iraqi economy, we are dealing with an even greater fear that the number of patients who present to the emergency room will become much greater than the system can cope with. Finally, our analysis tends to suggest that measures to reduce transmission should certainly be implemented, as our government did on March 9, by inhibiting people’s movement and social activities, unless strictly required. The most effective way to contain this viral outbreak in Iraq is probably to avoid close contact at the individual level and social meetings.

2020-11-25T00:00:00+01:00 ##submission.copyrightStatement## https://myresearchjournals.com/index.php/JCKHH/article/view/1403 2021-12-20T18:17:59+01:00 Madan Bhandari [email protected] Naveen Rao [email protected] Prasanna Narasimha Rao [email protected] B. J. Gopikrishna [email protected]

Fournier’s gangrene is rapidly progressive and potentially fatal infective necrotising fasciitis affecting the external genitalia, perineal or perianal regions. Among many sources of infection, perianal surgical manipulation is one of the major contributing factors. A 45-years diabetic patient who had recently undergone surgical debridement elsewhere to treat a perianal abscess visited SDM Ayurvedic hospital with mild scrotal pain and an unhealthy surgical wound. He was treated surgically with broad-spectrum antibiotics, strict control of hyperglycemia, regular minimum debridement of wound and dressing with a Yashtimadhu taila (an herbal oil with Glycyrrhiza glabra, Emblica officinalis, Sesamum indicum and cow milk as active ingredients) famous for its wound healing property. The patient gradually recovered and the wound was gradually healed with secondary intention.

2020-11-25T00:00:00+01:00 ##submission.copyrightStatement##