Evaluation of antibacterial activity of extract plant against Staphylococcus aureus and Candida albicans isolated from women

Mehrangiz Ghafari; Zahra Beigomi; Elham Javadian

Mehrangiz Ghafari Department of Pathology, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran
Zahra Beigomi Department of Physical Education, Zahedan University of Medical Sciences, Zahedan, Iran
Elham Javadian Department of Internal Medicine, School of Medicine, Amir al momenin Hospital, Zabol University of Medical Sciences, Zabol, Iran

Keywords: Staphylococcus aureus, Candida albicans , Extract plant, Rhazya stricta, Microdulition method

Abstract

Plants as sources of medicinal compounds from ancient times continue to play a major role in maintaining human health. The present study was performed to evaluate of antibacterial activity of Rhazya stricta extract prepared with different solvents on Staphylococcus aureus and Candida albicans isolated from women. The extracts of Rhazya stricta were prepared using a rotary device. The inhibitory concentration against S. aureus and c.albicans was determined using microdulition method. The results of this study showed that, the minimum inhibitory zone diameter of ethyl acetate extract against S.aureus was 1 mm and the maximum inhibitory zone diameter was 8 mm, the lowest inhibitory zone diameter of aqueous extract against S.aureus was 2 mm and the maximum inhibitory zone diameter of aqueous extract was equal to 12 mm. The results of this study showed that the highest inhibitory zone diameter was related to R.stricta extract prepared with ethanol solvent against C.albicans(18 mm) while the lowest inhibitory zone diameter was related to R. stricta extract prepared with ethyl acetate solvent (1 mm).The results of this study showed that the ethanolic extract of R. stricta showed the highest inhibitory properties of S. aureus and C. albicans that can be used in the treatment of infections caused by S.aureus.