Diabeted-1 treatment using Transdifferentiation

Abstract

In comparsion to any other country Indian have the highest number of diabetes patients. Because of less physical work, consumption of more fat and sugar, increased tension, number of over-weight and obese people in Indian are fast increasing. Because of obesity, occurrence of diabetes in people has increased with occurance of other diabetes associated problems like kidney failure , eye damage , atherosclerosis, coronary artery disease and other heart related problems. Auto-immune diseases are those diseases in which immune system starts damaging self cells of body. Type-1 diabetes is one of the auto-immune disease in which such type of antibodies are generat-ed by body which damages its own pancreatic a cells leading to decreased level of insulin pro-duction resulting in diabetes. On comparing with any western country Indians are becoming di-abetic about 10 years earlier on an average. Since treatment is not cost effective many people in India do not proper treatment and die because of diabetes. To cope with this problem research targeting to transdifferentiate liver cells to pancreatic a cell are in good progress. Results of these have given expectation to provide cost effective and efficient treatment for Type-1 diabetes in near future that most of the people can afford. In transdifferetiation factor are used to convert liver cells to pancreatic a cells so as to increase insulin production that can be used to cure Type-1 diabetes.