Association between Blood Eosinophil Count and Tissue Eosinophil Grading Among Patients Suffering From Sinonasal Polyposis Attending Tertiary Care Hospital

Abstract

Background: Present study aimed to evaluate the association between blood eosinophil count and tissue eosinophil grading among Patients suffering from Sinonasal Polyposis attending routine ENT OPD in Dr. RPGMC Tanda. Material and Methods: The present study was done as a hospital based cross sectional study in the department of ENT and Head and Neck Surgery, in Dr. RPGMC Kangra at Tanda. It was done in 30 patients of chronic rhinosinusitis with nasal polyposis (CRSwNP) from June 2018 to June 2019 who met the inclusion criteria. Data regarding Blood and Tissue eosinophil count was retrieved. Results: in the present study,there were a total of 30 patients out of which there were 16 males and 14 females. The mean age observed of patients was 42.47±13.68. Among the total, 17 patients were classified as Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis (ECRSwNP) while 13 were classified as Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis (NECRSwNP). There were 9 cases of ECRSwNP where tissue eosinophils were >10/HPF while 8 cases had less than 10 tissue eosinophils/HPF. Similarly 9 cases of NECRSwNP had less than 10 tissue eosinophils/HPF while 4 cases had tissue eosinophils were >10/HPF. The association between blood eosinophil count and tissue eosinophil grading was not significant with p value of 0.225. Conclusion: Present study concluded that there was no significant association of blood eosinophil count between NECRSwNP and ECRSwNP with tissue eosinophils.