Evaluation of Antibacterial and Anti Fungal Activity of Hexane and Methanol Extracts of Psoralea Corylifolea Seed.

Sharath K; Krishna Mohan G; Sandhya Rani M; Kowmudi V; Suresh N; Chintanippula Sai Rama Rao

Sharath K Faculty, Department of Pharmacognosy, Ganga College of Pharmacy, Telangana, India.
Krishna Mohan G Faculty, Department of Pharmacognosy, Center for pharmaceutical sciences, IST, JNTUH, Telangana, India.
Sandhya Rani M Faculty, Department of Pharmacognosy, Center for pharmaceutical sciences, IST, JNTUH, Telangana, India.
Kowmudi V Faculty, Department of Pharmacology, Ganga College of Pharmacy, Telangana, India.
Suresh N Faculty, Department of Pharmaceutics, Ganga College of Pharmacy, Telangana, India.
Chintanippula Sai Rama Rao Faculty, Department of Pharmaceutics, Ganga College of Pharmacy, Telangana, India.

Keywords: Psoralea Corylifolea, Candida albicans, Aspergillus niger, Staphylococcus aureus, antibacterial activity, antifungal activity.

Abstract

Objective: To evaluate antibacterial and antifungal activity of hexane and methanol extracts of Psoralea Corylifolea Seed. Method: Psoralea Corylifolia seeds were extracted by using different solvents hexane and methanol and the test extracts were assayed for antibacterial and antifungal activity. The antibacterial activity was tested against Staphylococcus aureus and antifungal activity was tested against Candida albicans and Aspergillus niger by agar well diffusion method and measuring the zone of Inhibition. Results: The hexane and methanol extracts of Psoralea corylifolia seed was very effective against Staphylococcus aureus, Candida albicans and Aspergillus niger. The results showed unique characters of the plant in inhibiting bacterial and fungal growth. Conclusion: In the present study antibacterial and anti fungal activity of hexane and methanol extracts of psoralea corylifolea seed was confirmed.