Study on the Wound Activity Potential on the Aqueous Extract of the Bark of Myrica esculenta Buch. and Ham.

Abstract

Myrica esculenta belongs to the family Myricaceae is a sub-temperate evergreen tree found throughout the mid-Himalayas, starting from about 1,300 meters and going up to about 2,100 meters. The tree yields a drupaceous fruit which is one of the tastiest wild fruits of the sub-Himalayan region. It is medium to large woody, evergreen, dioecious tree, 12 to 15 meters high; trunk girth, 92.5 cm; the male and the female trees have almost similar appearance.as ethnomedically bark was claimed to treat wounds and infection also, hence validation was done for its activity. The results show that the aqueous extract of Myrica esculenta has potent wound healing capacity as evident from the wound contraction and increased tensile strength. The results also indicated that Myrica esculenta extract possesses potent antioxidant activity by inhibiting lipid peroxidation and increase in the superoxide dismutase (SOD) and Catalase activity, besides antioxidant activity to understand the mechanism of wound healing activity.