Comparative Study of Anthelmintic Activity of Different Leaf Extracts of Tecoma stans (L.) on Adult Indian Earthworms

Abstract

Tecoma stans (L.) belonging to the family Bignoniaceae, is an ornamental tropical shrub predominately found in India, America, tropical and subtropical Africa, the Pacific islands, and Australia. The present study is an attempt to explore the anthelmintic activity of aqueous, alcoholic, hydro-alcoholic and methanolic extract (sohxlet) of leaves of Tecoma stans (L). The study was carried out for anthelmintic activity on adult Indian earthworm (Pheretima posthuma). All leaf extracts showed anthelmintic activity at 100, 200 and 500 μg/ml concentration. The activities were compared with the standard drug-Albendazole. Aqueous, alcoholic, hydro-alcoholic methanolic extract (sohxlet) of leaves of Tecoma stans showed better anthelmintic activity than the standard drugs. When the dose of the extract is increased, a gradual increase in anthelmintic activity was observed. Alcoholic extract showed better anthelmintic activity in comparison to the hydro-alcoholic, aqueous and methanolic extracts (sohxlet) of Tecoma stans. The data were verified as statistically significant by using one way ANOVA at 1 % level of significance (p less than 0.001).