Recent Advancements for Triazoles as Anticancer Agents

Yashwant; B. K. Sharma; B. Srivastava; Vandana Sharma

Yashwant School of Pharmaceutical Sciences, Jaipur National University, Jaipur, 302025, India
B. K. Sharma School of Pharmaceutical Sciences, Jaipur National University, Jaipur, 302025, India
B. Srivastava School of Pharmaceutical Sciences, Jaipur National University, Jaipur, 302025, India
Vandana Sharma School of Pharmaceutical Sciences, Jaipur National University, Jaipur, 302025, India

Keywords: Anticancer, triazoles, antitumor, C-nucleoside.

Abstract

Cancer is one of the leading causes of death in the world. The present work gives the recent advancements for triazoles as anticancer agents. Triazoles are known to have a large spectrum of potential anticancer, antimitotic and antifungal properties. With an improved understanding of the genes and pathways responsible for cancer initiation and progression, cancer drug development has undergone a paradigm change in recent years, from predominantly cytotoxic agent-based therapy to therapy aimed at molecular and genetic targets