Synthesis, Characterization and Antimicrobial Screening Of 3-(1HBenzo[ D]Imidazol-2-Ylsulfanyl) Methyl-4-[Phenoxy(Phenyl) Acetamido)-5-Mercapto-1,2,4-Triazole and Related Aryloxy Compounds

Abstract

A series of new 1H-benzo[d]imidazole derivatives of 3,4-substituted triazole. 3-(1H-Benzo[d]imidazol-2- ylsulfanyl)methyl-4-[phenyloxy(phenylacetamido)]-5-mercapto-1,2,4-triazole and related aryloxy compounds were synthesised, analysed and characterised by FTIR, 1HNMR and elemental analysis. These compounds were screened for antibacterial and antifungal activity. The antibacterial activities were compared against chlorophenicol and antifungal activity with mycostalin. Some triazole derivatives showed a little antibacterial but appreciable antifungal activity.