A REVIEW ON MICRO-BALLOONS

Gupta B; Mishra R; Mishra I

Gupta B Department of Pharmaceutical Sciences, Shri Ram Murti Smarak College of Engineering and Technology, Bareilly, U. P., India
Mishra R Department of Pharmaceutical Sciences, Shri Ram Murti Smarak College of Engineering and Technology, Bareilly, U. P., India
Mishra I Department of Pharmaceutical Sciences, Shri Ram Murti Smarak College of Engineering and Technology, Bareilly, U. P., India

Keywords: Micro-balloons, Preparation, Evaluation, Gastric retention, Bioavailability, Chitosan

Abstract

Oral prolonged release systems are manufactured to release the drug in-vivo with privies to enhance bioavailability, diminish untoward effects
and enhance effectiveness of drugs. Microballoons or hollow microspheres are anticipated to persist buoyant in a permanent way upon the gastric
ingredients. The various formulations comprise unfilled microspheres, powders, capsules, tablets and laminated films. Micro-balloons are
distinctly attaining attention due to their immense significance in the drug targeting to the stomach. These floating micro-balloons have the
convenience that they stay buoyant and circulate uniformly over the gastric ingredients to refrain the variations of gastric emptying and release
the drug for extended period of time. Multiparticulate particles of low density can efficiently prolong the gastric retention time of drugs. This
article provides an insight of fabrication and methods of evaluation of micro-balloons.